small microscope

Online Short Course Homocysteinemias (Nov 2021)

Class Description

Nov 1st thru Nov 12th, 2021- registration is now open!

Price: $75 (APPs, GCs, MD trainees), $150 (practicing physicians), or $250 (corporate)

Offered again Nov 1-12, 2021 (registration opens Sept 1, 2021)

Approved for 4.0 AMA PRA Category. 1 Credits™/ 4.0 AAPA Category 1 CME credits/ 4.0 ANCC Contact Hours/4.0 Credits for Dieticians


This online short course is spread out over two weeks to accommodate a full-time working schedule. It includes a mix of learning experiences - six short live sessions (with a choice of 9:00am or 5:00pm ET), brief pre-recorded video seminars to review when convenient, and homework exercises. The curriculum also includes a live patient presentation and a special session addressing the role of the non-physician in patient diagnosis/management. The duration of the course allows a comprehensive review of the topic and the opportunity to apply the learned principles to several clinical situations.

The course targets primarily (but not exclusively) advanced practice providers and clinicians who:

  • have a science background
  • have had no/limited formal training in genetic metabolic disease
  • are interested, or are involved, in the diagnosis/management of patients with inborn errors of metabolism

Nurses/nurse practitioners, physician assistants, genetic counselors, and dietitians, and their trainees, are especially welcome, but physician, research, and corporate applicants are invited to participate as well.


  • Mark Korson, MD
  • Lynne Wolfe, MS, CRNP, BC
  • Patient-teacher(s), to be announced


At the end of each training, attendees should be able to:

  1. Detail the varied phenotypes of the organic acidemias
  2. Review the disease physiology and link it to the clinical and biochemical phenotypes.
  3. Characterize the biochemical derangements that typify the organic acidemias and how they apply to diagnosis and therapeutic monitoring.
  4. Employ current guidelines for the diagnosis and management of patients with an organic acidemia.
  5. Formulate in conjunction with other team members specific assessments and care-plans of patients with suspected or proven organic acidemias.


Each course is spaced out over two weeks with six live sessions to support working schedules and enhance recall. Once you register for either the 9am or 5pm (ET) track you will be provided login information to access a restricted webpage that will house all the documents, links, videos and material for the course.

Week One
Monday (<30 min remote session, choice of 9:00am or 5:00pm ET)

  • Introduction
  • Assignment of homework (<1 hour), due Wednesday
    • View recorded sessions: Physiology, Biochemistry
    • Case problems

Wednesday (30-40 min remote session, choice of 9:00am or 5:00pm ET)

  • Q+A for homework recorded sessions
  • Review of case problems
  • Assignment of homework (<1 hour), due Friday
    • View recorded sessions: Clinical Phenotype, Genetics
    • Case problems

Friday (30-40 min remote session, choice of 9:00am or 5:00pm ET)

  • Q+A for homework recorded sessions
  • Review of case problems
  • Assignment of homework (<1 hour), due Monday
    • View recorded sessions: Diagnostic testing, Newborn screening
    • Case problems

Week Two
Monday (60 min remote session, choice of 9:00am or 5:00pm ET)

  • Patient presentation
  • Q+A for homework recorded sessions
  • Review of case problems
  • Assignment of homework (<1 hour), due Friday
    • View recorded session: Management
    • Case problems

Wednesday (45 min remote session, choice of 9:00am or 5:00pm ET)

  • Role of the APP in the clinic relative to this disease group

Friday (45 min remote session, choice of 9:00am or 5:00pm ET)

  • Q+A for homework recorded sessions
  • Review of case problems
  • Conclusion, evaluation

A syllabus will be provided to all participants.


  1. The topics are relevant.
  2. The presentation is pitched appropriately for the audience.
  3. The format is clinical and practical.
  4. Where possible, the patient story is included in the program (live +/- recorded presentations).
  5. Teaching is interactive and includes engaging the audience throughout with questions and case reviews.
  6. Through a combination of didactic teaching and case workshops, attendees are given the opportunity to apply the principles they have learned to (adapted) real-life cases, empowering them to better tackle such medical challenges in their clinical practice
  7. Repeated learning over time is more likely to be associated with a long-term retention of the material.
  8. All essential teaching slides are provided in a handout to attendees.


Continuing Education Credits:

Joint Accreditation Statement Jointly Accreditated Provider.jpg

In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and Virtual Medical Practice.  Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education  The Postgraduate Institute for Medicine designates this live activity for a maximum of 4.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Continuing Nursing Education  The maximum number of hours awarded for this Continuing Nursing Education activity is 4.0 contact hours.

AAPA Credit Designation Statement   AAPA CME.png

Postgraduate Institute for Medicine has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 4.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.

Continuing Dietician Education  This program offers 4.0 CPEUs for dieticians.

Computer System Requirements:

Zoom & Youtube account with access to DSL 15  Mbps or higher, Fiber, 4g, or 5g internet access. The higher the Mbps, the better the quality.

Disclosure of Conflicts of Interest:

Postgraduate Institute for Medicine (PIM) requires faculty, planners, and others in control of educational content to disclose all their financial relationships with ineligible companies. All identified conflicts of interest (COI) are thoroughly vetted and mitigated according to PIM policy.  PIM is committed to providing its learners with high quality accredited continuing education activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company. The faculty reported the following relevant financial relationships with ineligible entities related to the educational content of this CE activity:

  • Mark Korson, MD has the following to report:
    • Recordati Rare Diseases - grant recipient
    • Alnylam Pharmaceuticals, Solace Nutrition, Tessera Therapeutics - consultant
    • HemoShear Therapeutics - DMC member
    • Moderna Therapeutics - consultant (no longer active)
  • Lynne Wolfe, MS, CRNP, BC, has nothing to disclose.
  • Patient-teacher(s), to be announced
  • The PIM planners and others have nothing to disclose.

DIsclosure of Unlabeled Use:

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA.  The planners of this activity do not recommend the use of any agent outside of the labeled indications.  The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners.  Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development.  The information presented in this activity is not meant to serve as a guideline for patient management.  Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.


Jointly provided by Postgraduate Institute for Medicine and Virtual Medical Practice.

This activity is supported by an independent educational grant from Recordati Rare Diseases.

....when enrolling, please let us know if you will be attending the 9am or 5pm (ET) course

Back to Educational Events